Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

In a basement lab in Brandeis' Rosenstiel building, a refrigerator-sized microscope dominates a small, windowless room. On its surface, it looks like a featureless white box. Yet inside, it's a study ...

Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo-EM), Leonid ...

A comparison of experimental annular dark field (ADF)-scanning transmission electron microscopy (STEM) and electron ptychography in uncorrected and aberration-corrected electron microscopes. In the ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

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A new imaging technique enables atomic-scale clarity with compact, low-energy electron microscopes, making high-resolution microscopy more accessible worldwide. (Nanowerk News) A team of researchers ...